Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

Aging and cancer are deeply intertwined: advancing age is the single largest risk factor for most malignancies, and many of the molecular processes that ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Researchers at the University Hospital Bonn have developed a humanized mouse model for myofibrillar myopathy type 6 (MFM6), revealing that impaired autophagy driven by a defective BAG3 protein leads ...

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...