Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which ...

Researchers in Spain have found that chaperone-mediated autophagy, a selective protein cleanup process, is markedly reduced in the motor neurons of ALS patients. The deficiency may contribute to toxic ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesine Convergence of impaired autophagy and synaptic dysfunction across ...

Postmenopausal women are at higher risk for both osteoporosis and depression, yet no single treatment effectively addresses both conditions because their shared biological basis remains poorly ...

From PCR and CRISPR to autophagy and targeted cancer therapies, scientists share the discoveries that shaped their work and ...

Researchers from City of Hope(R) , one of the largest and most advanced cancer research and treatment organizations in the United Sta ...

Illustration of human lymphocytes. (Ruslanas Baranauskas/Science Photo Library) Defeating obesity is rarely easy. For many ...

Autism and Alzheimer’s disease have long occupied separate corners of neuroscience. One is diagnosed in childhood; the other ...

Aging and cancer are deeply intertwined: advancing age is the single largest risk factor for most malignancies, and many of the molecular processes that ...